Two new withanolide lactones from flos daturae.

نویسندگان

  • Hai-Xue Kuang
  • Bing-You Yang
  • Yong-Gang Xia
  • Qiu-Hong Wang
چکیده

Chemical investigation of the 50% ethanol eluate fraction from a macroporous resin of flowers of Datura metel L. collected in the Jiangsu Province of China resulted in the isolation of two new withanolides, baimantuoluoline G (1) and baimantuoluoside H (2). Their structures were elucidated as (12β,6β,22R)-1,10-seco-6,12,27-trihydroxy-26-oxo-witha-3,5,24-trienolide-1-oic acid-ε-lactone (1) and (5β,6α,12β,22R)-5,6,12,27-tetra-hydroxy-1,26-dioxo-witha-2,24-dienolide-27-O-β-glucopyranoside (2) on the basis of extensive spectroscopic analysis (1D, 2D-NMR and HRESIMS) and chemical studies.

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عنوان ژورنال:
  • Molecules

دوره 16 7  شماره 

صفحات  -

تاریخ انتشار 2011